Vaccine-related benefits may be threatened by combinedvaccine- and antibiotic-driven selective pressure.
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The vaccine is administered by GPs using a five-in-one combinedvaccine.
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Tests in rabbits and mice suggested the combinedvaccine would protect better than either of the older vaccines, they said.
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It is concluded that this combinedvaccine against hepatitis A and B, administered according to a two-dose schedule, is well-tolerated and highly immunogenic.
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The finding is not a reason for parents to avoid the combinedvaccine, and is actually "reassuring," said one expert not involved in the study.
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The combinationvaccine also protects against diphtheria and tetanus.
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A similar combinationvaccine is given to children in five doses between two months and six years of age.
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We report an evaluation of the short-term safety of a pediatric bivalent combinationvaccine containing RECOMBIVAXHB and Liquid PedvaxHIB, COMVAX.
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This combinationvaccine induced low Hib antibody responses when compared to other studies in which PRP-T was mixed with acellular or whole-cell pertussis vaccines.
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Our results showed that the combinationvaccine was as effective as the currently used vaccines (PCV7 and PPV23).
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But it's been less clear if that risk also applies to newer versions in combinedvaccines, according to study author Yuelian Sun, from Aarhus University.
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Furthermore, no objective strategies currently exist to select actual viral variants that should be included or excluded in polyvalentvaccines.
Uso de multivalent vaccine en inglés
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Thus, the enzyme has potential as a component of a multivalentvaccine against schistosomiasis.
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No single viral variant can induce sufficiently broad immunity, and incorporating all known naturally circulating variants into one multivalentvaccine is not feasible.
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These observations support the feasibility of a multivalentvaccine against shigellosis and ETEC diarrhea consisting of multiple Shigella live vectors expressing relevant ETEC antigens.
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These results have implications for the design of multivalentvaccines.
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Furthermore, to reduce the burden of vaccination, the development of multivalentvaccines is highly desirable.
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Our study suggests that multivalentvaccines may be more suitable in this setting, especially for HIV-infected individuals.
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The use of such multivalentvaccines did not show overt immune interference in comparison with monovalent vaccines.
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Collectively, our results support previous reports about the potential benefit of EV-A71 vaccine but highlight the necessity of multivalentvaccines to control HFMD.